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NKX3-2 / BAPX1 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | P78367 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35kDa |
| Dilution | IHC-P (5 µg/ml), WB (0.5-1 µg/ml), |
| Gene ID | 579 |
|---|---|
| Other Names | Homeobox protein Nkx-3.2, Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, NKX3-2, BAPX1, NKX3B |
| Target/Specificity | Human NKX3-2 / BAPX1. BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | NKX3-2 / BAPX1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NKX3-2 |
|---|---|
| Synonyms | BAPX1, NKX3B |
| Function | Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity).
References
Tribioli C.,et al.Gene 203:225-233(1997).
Yoshiura K.,et al.Genomics 45:425-428(1997).
Tribioli C.,et al.Mech. Dev. 65:145-162(1997).
Hellemans J.,et al.Am. J. Hum. Genet. 85:916-922(2009).
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