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>   home   >   Products   >   Primary Antibodies   >   NKX3-2 / BAPX1 Antibody (Internal)   

NKX3-2 / BAPX1 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - NKX3-2 / BAPX1 Antibody (Internal) ALS14766
    Immunofluorescence of BAPX1 in mouse brain tissue with BAPX1 antibody at 20 ug/ml.
  • WB - NKX3-2 / BAPX1 Antibody (Internal) ALS14766
    Western blot analysis of BAPX1 in human brain tissue lysate with BAPX1 antibody at 1 ug/ml in...
  • IHC - NKX3-2 / BAPX1 Antibody (Internal) ALS14766
    Anti-NKX3-2 antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P78367
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Dilution IHC-P (5 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Gene ID 579
Other Names Homeobox protein Nkx-3.2, Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, NKX3-2, BAPX1, NKX3B
Target/Specificity Human NKX3-2 / BAPX1. BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsNKX3-2 / BAPX1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX3-2
Synonyms BAPX1, NKX3B
Function Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton
Citations (0)

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Background

Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity).

References

Tribioli C.,et al.Gene 203:225-233(1997).
Yoshiura K.,et al.Genomics 45:425-428(1997).
Tribioli C.,et al.Mech. Dev. 65:145-162(1997).
Hellemans J.,et al.Am. J. Hum. Genet. 85:916-922(2009).

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$ 395.00
Cat# ALS14766
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