|Application ||WB, IHC-P, IF|
|Calculated MW||54206 Da|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Myocardial zonula adherens protein, GRINL1A upstream protein, Gup, MYZAP, MYOZAP|
|Target/Specificity||Human GCOM1. Multiple isoforms of MYOZAP are known to exist.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||MYZAP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in cellular signaling via Rho-related GTP- binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, Z line. Cell junction. Note=Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disks. Colocalizes with F-actin. Colocalizes with cortical actin (By similarity).|
|Tissue Location||Detected in heart, liver, skeletal muscle, placenta, small intestine, lung, prostate and testis|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.