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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SNCG / Gamma-Synuclein Antibody (aa78-127)   

SNCG / Gamma-Synuclein Antibody (aa78-127)

Rabbit Polyclonal Antibody

     
  • WB - SNCG / Gamma-Synuclein Antibody (aa78-127) ALS14773
    Western blot of extracts from HT29 cells, using Synuclein gamma Antibody.
  • IHC - SNCG / Gamma-Synuclein Antibody (aa78-127) ALS14773
    Anti-SNCG antibody IHC of human adrenal cortex.
  • IHC - SNCG / Gamma-Synuclein Antibody (aa78-127) ALS14773
    Anti-SNCG antibody IHC of human brain, cortex neurons.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O76070
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 13kDa
Dilution ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 6623
Other Names Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, SNCG, BCSG1, PERSYN, PRSN
Target/Specificity Synuclein gamma Antibody detects endogenous levels of total Synuclein gamma protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsSNCG / Gamma-Synuclein Antibody (aa78-127) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNCG
Synonyms BCSG1, PERSYN, PRSN
Function Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Cellular Location Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle
Tissue Location Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung
Volume 50 µl
Research Areas
Citations (0)

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Background

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).

References

Ji H.,et al.Cancer Res. 57:759-764(1997).
Ninkina N.N.,et al.Hum. Mol. Genet. 7:1417-1424(1998).
Lavedan C.,et al.Hum. Genet. 103:106-112(1998).
Han C.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Pronin A.N.,et al.J. Biol. Chem. 275:26515-26522(2000).

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$ 395.00
Cat# ALS14773
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