|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:5000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||MAP/microtubule affinity-regulating kinase 3, 184.108.40.206, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, MARK3, CTAK1, EMK2|
|Target/Specificity||MARK3 Antibody detects endogenous levels of total MARK3 protein.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||C-TAK1 / MARK3 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.|
|Cellular Location||Cell membrane; Peripheral membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.
Peng C.Y.,et al.Cell Growth Differ. 9:197-208(1998).
Waggoner S.N.,et al.Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
Sun T.-Q.,et al.Nat. Cell Biol. 3:628-636(2001).
Drewes G.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Maheshwari K.K.,et al.Submitted (JAN-1992) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.