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> home > Products > Primary Antibodies > Antibody Collections > Anti-Wnt-Pathway (plus Lgr5) Antibodies > CSNK1E / CK1 Epsilon Antibody (aa276-325)
CSNK1E / CK1 Epsilon Antibody (aa276-325)
Rabbit Polyclonal Antibody
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Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P49674 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47315 Da |
| Dilution | ELISA (1:20000), IF (1:100-1:500), IHC-P (15 µg/ml), WB (1:500-1:1000) , |
| Gene ID | 102800317;1454 |
|---|---|
| Other Names | Casein kinase I isoform epsilon, CKI-epsilon, CKIe, 2.7.11.1, CSNK1E |
| Target/Specificity | CKI-epsilon Antibody detects endogenous levels of total CKI-epsilon protein. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | CSNK1E / CK1 Epsilon Antibody (aa276-325) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CSNK1E |
|---|---|
| Function | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (Probable). Participates in Wnt signaling (PubMed:12556519, PubMed:23413191). Phosphorylates DVL1 (PubMed:12556519). Phosphorylates DVL2 (PubMed:23413191). Phosphorylates NEDD9/HEF1 (By similarity). Central component of the circadian clock (PubMed:16790549). In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation (PubMed:15917222, PubMed:16790549). Controls PER1 and PER2 nuclear transport and degradation (By similarity). Inhibits cytokine-induced granuloytic differentiation (PubMed:15070676). |
| Cellular Location | Cytoplasm. Nucleus. |
| Tissue Location | Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle Expressed in monocytes and lymphocytes but not in granulocytes |
| Volume | 50 µl |
Research Areas
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