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FOXD3 Antibody (aa211-260)

Rabbit Polyclonal Antibody

     
  • WB - FOXD3 Antibody (aa211-260) ALS14786
    Western blot of extracts from HUVEC/293 cells, using FOXD3 Antibody.
  • IHC - FOXD3 Antibody (aa211-260) ALS14786
    Anti-FOXD3 antibody IHC of human heart.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UJU5
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Dilution ELISA (1:5000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 27022
Other Names Forkhead box protein D3, HNF3/FH transcription factor genesis, FOXD3, HFH2
Target/Specificity FOXD3 Antibody detects endogenous levels of total FOXD3 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsFOXD3 Antibody (aa211-260) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXD3
Synonyms HFH2
Function Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Cellular Location Nucleus.
Tissue Location Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined
Volume 50 µl
Research Areas
Citations (0)

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Background

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

References

Ramsey H.C.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Hromas R.,et al.Blood 81:2854-2859(1993).
Guo Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).
Alkhateeb A.,et al.J. Invest. Dermatol. 125:388-391(2005).

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$ 395.00
Cat# ALS14786
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