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FE65L1 / APBB2 Antibody (aa471-520)

Rabbit Polyclonal Antibody

     
  • WB - FE65L1 / APBB2 Antibody (aa471-520) ALS14788
    Western blot of extracts from LOVO cells, using APBB2 Antibody.
    detail
  • IHC - FE65L1 / APBB2 Antibody (aa471-520) ALS14788
    Anti-APBB2 antibody IHC of human adrenal cortex.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q92870
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 83kDa
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 323
Other Names Amyloid beta A4 precursor protein-binding family B member 2, Protein Fe65-like 1, APBB2, FE65L, FE65L1
Target/Specificity APBB2 Antibody detects endogenous levels of total APBB2 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsFE65L1 / APBB2 Antibody (aa471-520) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APBB2 (HGNC:582)
Function Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity). Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (By similarity). Activates transcription of APP (PubMed:14527950).
Cellular Location Endoplasmic reticulum. Golgi apparatus. Early endosome
Tissue Location Widely expressed..
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

May modulate the internalization of beta-amyloid precursor protein.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Guenette S.Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:10832-10837(1996).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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Discontinued
Cat# ALS14788
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