|Application ||WB, IHC-P, E, IP|
|Dilution||IHC-P (1:200), WB (1:2000),|
|Other Names||Extracellular superoxide dismutase [Cu-Zn], EC-SOD, 220.127.116.11, SOD3|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SOD3 Antibody (clone 1H12) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.|
|Cellular Location||Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium|
|Tissue Location||Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid|
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Provided below are standard protocols that you may find useful for product applications.
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Hjalmarsson K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6340-6344(1987).
Folz R.J.,et al.Genomics 22:162-171(1994).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Adachi T.,et al.Free Radic. Biol. Med. 13:205-210(1992).
Nozik-Grayck E.,et al.Int. J. Biochem. Cell Biol. 37:2466-2471(2005).
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