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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MKNK1 / MNK1 Antibody (clone 24C2)   

MKNK1 / MNK1 Antibody (clone 24C2)

Mouse Monoclonal Antibody

     
  • WB - MKNK1 / MNK1 Antibody (clone 24C2) ALS14812
    0
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BUB5
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Clone Names 24C2
Calculated MW 51kDa
Dilution IHC-P (1:400), WB (1:1000),
Additional Information
Gene ID 8569
Other Names MAP kinase-interacting serine/threonine-protein kinase 1, 2.7.11.1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, MKNK1, MNK1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsMKNK1 / MNK1 Antibody (clone 24C2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MKNK1
Synonyms MNK1
Function May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
Cellular Location Isoform 2: Cytoplasm.
Tissue Location Ubiquitous..
Volume 50 µl
Research Areas
Citations (0)

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Background

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.

References

Fukunaga R.,et al.EMBO J. 16:1921-1933(1997).
Knauf U.,et al.Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A.,et al.Exp. Cell Res. 299:343-355(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS14812
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