|Application ||WB, IHC-P, IF, ICC|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||UPF0577 protein KIAA1324, Estrogen-induced gene 121 protein, KIAA1324, EIG121|
|Target/Specificity||Human KIAA1324. At least four isoforms of EIG121 known to exist. EIG121 antibody is predicted to not cross-react with other UPF0577 protein family members.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||KIAA1324 / maba1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein|
|Tissue Location||Expressed in normal endometrium but overexpressed in endometroid tumors|
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Provided below are standard protocols that you may find useful for product applications.
May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Gregory S.G.,et al.Nature 441:315-321(2006).
Nagase T.,et al.DNA Res. 7:65-73(2000).
Deng L.,et al.Clin. Cancer Res. 11:8258-8264(2005).
Deng L.,et al.Cell Death Dis. 1:E32-E32(2010).
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