|Application ||WB, IHC-P|
|Dilution||IHC-P (1:400), WB (1:2000),|
|Other Names||Serum paraoxonase/lactonase 3, 22.214.171.124, 126.96.36.199, 188.8.131.52, PON3|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||PON3 Antibody (clone 5G11) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.|
|Cellular Location||Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
Reddy S.T.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Draganov D.I.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
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