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SYT6 / Synaptotagmin 6 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q5T7P8 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57kDa |
| Dilution | IHC-P (1:200), WB (1:2000), |
| Gene ID | 148281 |
|---|---|
| Other Names | Synaptotagmin-6, Synaptotagmin VI, SytVI, SYT6 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | SYT6 / Synaptotagmin 6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SYT6 |
|---|---|
| Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9R0N8}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9R0N8} [Isoform 2]: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9R0N8}. Cell membrane {ECO:0000250|UniProtKB:Q9R0N8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9R0N8} |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)- regulation of exocytosis in acrosomal reaction in sperm (By similarity).
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011).
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