|Application ||WB, IHC-P, IHC-Fr|
|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Chicken, Sheep, Xenopus, Bovine, Guinea Pig, Dog|
|Dilution||IHC-Fr (1:50-1:100), IHC-P (10 µg/ml), WB (1:100-1:500)|
|Other Names||Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, KIAA0845, NFH|
|Target/Specificity||Reacts exclusively with the phosphorylated isoform of the 200 kD neurofilament protein.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||NEFH / NF-H Antibody (clone RNF404) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.|
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Provided below are standard protocols that you may find useful for product applications.
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.
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Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
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