|Application ||WB, IHC-P, IHC-Fr|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Chicken, Sheep, Xenopus, Bovine, Guinea Pig, Dog|
|Dilution||IHC-Fr (1:50-1:100), IHC-P (10 µg/ml), WB (1:100-1:500)|
|Other Names||Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, KIAA0845, NFH|
|Target/Specificity||Reacts exclusively with the phosphorylated isoform of the 200 kD neurofilament protein.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||NEFH / NF-H Antibody (clone RNF405) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.
Lees J.F.,et al.EMBO J. 7:1947-1955(1988).
Zhu Y.,et al.Beijing Yi Ke Da Xue Xue Bao 31:531-531(1999).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
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