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EIF4B Antibody (aa150-200)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P23588 |
| Reactivity | Human, Mouse, Rat, Chicken, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 69kDa |
| Dilution | IHC-P (10 µg/ml), WB (0.25-0.5 µg/ml), |
| Gene ID | 1975 |
|---|---|
| Other Names | Eukaryotic translation initiation factor 4B, eIF-4B, EIF4B |
| Target/Specificity | Human EIF4B |
| Reconstitution & Storage | Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C. |
| Precautions | EIF4B Antibody (aa150-200) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EIF4B |
|---|---|
| Function | Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
References
Milburn S.C.,et al.EMBO J. 9:2783-2790(1990).
Yokoyama K.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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