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TOMM22 / TOM22 Antibody (clone 4G4)

Mouse Monoclonal Antibody

     
  • WB - TOMM22 / TOM22 Antibody (clone 4G4) ALS14896
    LS-B7222 Western blot of TOMM22 expression in PC-12.
  • WB - TOMM22 / TOM22 Antibody (clone 4G4) ALS14896
    ALS14896 Western blot of TOMM22 expression in Raw 264.7.
  • WB - TOMM22 / TOM22 Antibody (clone 4G4) ALS14896
    ALS14896 Western blot of TOMM22 expression in NIH/3T3.
  • IF - TOMM22 / TOM22 Antibody (clone 4G4) ALS14896
    Immunofluorescence of monoclonal antibody to TOMM22 on HeLa cell. [antibody concentration 10 ug/ml]
  • IHC - TOMM22 / TOM22 Antibody (clone 4G4) ALS14896
    Anti-TOMM22 antibody IHC of human liver, hepatocytes.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9NS69
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Clone Names 4G4
Calculated MW 16kDa
Dilution IF (10 µg/ml), IHC-P (10 µg/ml),
Additional Information
Gene ID 56993
Other Names Mitochondrial import receptor subunit TOM22 homolog, hTom22, 1C9-2, Translocase of outer membrane 22 kDa subunit homolog, TOMM22, TOM22
Target/Specificity Human TOMM22
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTOMM22 / TOM22 Antibody (clone 4G4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TOMM22
Synonyms TOM22
Function Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Background

Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.

References

Yano M.,et al.Mol. Cell. Biol. 20:7205-7213(2000).
Saeki K.,et al.J. Biol. Chem. 275:31996-32002(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Bienvenut W.V.,et al.Submitted (JUN-2005) to UniProtKB.

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$ 450.00
Cat# ALS14896
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