|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IF (10 µg/ml), IHC-P (10 µg/ml),|
|Other Names||Mitochondrial import receptor subunit TOM22 homolog, hTom22, 1C9-2, Translocase of outer membrane 22 kDa subunit homolog, TOMM22, TOM22|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||TOMM22 / TOM22 Antibody (clone 4G4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.|
|Cellular Location||Mitochondrion outer membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.
Yano M.,et al.Mol. Cell. Biol. 20:7205-7213(2000).
Saeki K.,et al.J. Biol. Chem. 275:31996-32002(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Bienvenut W.V.,et al.Submitted (JUN-2005) to UniProtKB.
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