|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Hamster, Horse, Dog|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1, ATP1B1, ATP1B|
|Target/Specificity||Human ATP1B1. This antibody is expected to recognize both reported isoforms (NP_001668.1; NP_001001787.1).|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||ATP1B1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Found in most tissues.|
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Provided below are standard protocols that you may find useful for product applications.
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Kawakami K.,et al.Nucleic Acids Res. 14:2833-2844(1986).
Lane L.K.,et al.Genomics 5:445-453(1989).
Ruiz A.,et al.Gene 155:179-184(1995).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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