|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Monkey|
|Dilution||IHC-P (10 µg/ml), WB (0-1 µg/ml),|
|Other Names||Eukaryotic translation initiation factor 4B, eIF-4B, EIF4B|
|Reconstitution & Storage||Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.|
|Precautions||EIF4B Antibody (aa570-630) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.|
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Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Milburn S.C.,et al.EMBO J. 9:2783-2790(1990).
Yokoyama K.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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