KCNJ9 / Kir3.3 / GIRK3 Antibody (aa61-110)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q92806 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 44kDa |
Dilution | ELISA (1:40000), IHC-P (5 µg/ml), WB (1:500-1:1000) |
Gene ID | 3765 |
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Other Names | G protein-activated inward rectifier potassium channel 3, GIRK-3, Inward rectifier K(+) channel Kir3.3, Potassium channel, inwardly rectifying subfamily J member 9, KCNJ9, GIRK3 |
Target/Specificity | KCNJ9 Antibody detects endogenous levels of total KCNJ9 protein. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | KCNJ9 / Kir3.3 / GIRK3 Antibody (aa61-110) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KCNJ9 |
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Synonyms | GIRK3 |
Function | This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity). |
Cellular Location | Membrane; Multi-pass membrane protein. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity).
References
Schoots O.,et al.Cell. Signal. 11:871-883(1999).
Vaughn J.,et al.Biochem. Biophys. Res. Commun. 274:302-309(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
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