|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Xenopus, Bovine, Dog|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml), WB (0.2-0.5 µg/ml)|
|Other Names||Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, SMADIP1, Zinc finger homeobox protein 1b, ZEB2, KIAA0569, SIP1, ZFHX1B, ZFX1B|
|Target/Specificity||Human ZEB2. This antibody is expected to recognize both reported isoforms (NP_055610.1; NP_001165124.1).|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||ZEB2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0569, SIP1, ZFHX1B, ZFX1B|
|Function||Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin.|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin.
Cacheux V.,et al.Hum. Mol. Genet. 10:1503-1510(2001).
Wakamatsu N.,et al.Nat. Genet. 27:369-370(2001).
Nagase T.,et al.DNA Res. 5:31-39(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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