|Application ||WB, IHC-P|
|Dilution||IHC-P (1:100), WB (1:500-1:5000),|
|Other Names||ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, ABC-1, ATP-binding cassette 1, Cholesterol efflux regulatory protein, ABCA1, ABC1, CERP|
|Target/Specificity||This Polyclonal antibody is directed against human ABCA1 protein. The product was purified from serum by protein A chromatography. Expect reactivity with human ABCA1. Cross-reactivity with ABCA1 from other sources has not been determined.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||ABCA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed, but most abundant in macrophages|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
Santamarina-Fojo S.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:7987-7992(2000).
Schwartz K.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Qiu Y.,et al.Genomics 73:66-76(2001).
Tanaka A.R.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
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