|Application ||IHC-P, E|
|Reactivity||Human, Rabbit, Monkey, Bovine|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml),|
|Other Names||InaD-like protein, Inadl protein, hINADL, Pals1-associated tight junction protein, Protein associated to tight junctions, INADL, PATJ|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||INADL / PATJ Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.|
|Cellular Location||Membrane. Cell junction, tight junction. Apical cell membrane. Cytoplasm, perinuclear region Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane.|
|Tissue Location||Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.
Philipp S.,et al.FEBS Lett. 413:243-248(1997).
Soejima H.,et al.Genomics 74:115-120(2001).
Roh M.H.,et al.J. Cell Biol. 157:161-172(2002).
Gregory S.G.,et al.Nature 441:315-321(2006).
Lemmers C.,et al.J. Biol. Chem. 277:25408-25415(2002).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.