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APOBEC3A Antibody (Internal)

Goat Polyclonal Antibody

  • IHC - APOBEC3A Antibody (Internal) ALS14952
    Anti-APOBEC3A antibody IHC of human tonsil.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31941
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 23012 Da
Dilution ELISA (1:8000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 100913187;200315
Other Names DNA dC->dU-editing enzyme APOBEC-3A, A3A, 3.5.4.-, Phorbolin-1, APOBEC3A
Target/Specificity Human APOBEC3A.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsAPOBEC3A Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno- associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia.
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$ 395.00
Cat# ALS14952
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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