|Application ||IHC-P, E|
|Reactivity||Human, Rat, Rabbit, Monkey, Horse|
|Dilution||ELISA (1:4000), IHC-P (3.75 µg/ml),|
|Other Names||E3 ubiquitin-protein ligase MARCH7, 6.3.2.-, Axotrophin, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, MARCH-VII, RING finger protein 177, MARCH7, AXOT, RNF177|
|Target/Specificity||Human MARCH7 / Axotrophin.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||MARCH7 / Axotrophin Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.|
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Provided below are standard protocols that you may find useful for product applications.
E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Metcalfe S.M.,et al.FEBS Lett. 579:609-614(2005).
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