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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL17A Antibody   

IL17A Antibody

Rabbit Polyclonal Antibody

     
  • WB - IL17A Antibody ALS14963
    Western Blot (non-reducing) of IL-17 antibody ALS14963
  • WB - IL17A Antibody ALS14963
    Western Blot (reducing) of IL-17 antibody ALS14963
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Neut
Primary Accession Q16552
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 18kDa
Dilution ELISA (0.5-2 µg/ml), IHC-P (5 µg/ml), Neut (0.9-1.3 µg/ml), WB (0.1-0.2 µg/ml) ,
Additional Information
Gene ID 3605
Other Names Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A, CTLA8, IL17
Target/Specificity Human IL-17A
Reconstitution & Storage Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
PrecautionsIL17A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17A
Synonyms CTLA8, IL17
Function Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
Cellular Location Secreted.
Tissue Location Restricted to activated memory T-cells.
Research Areas
Citations (0)

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Background

Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

References

Fossiez F.,et al.J. Exp. Med. 183:2593-2603(1996).
Yao Z.,et al.J. Immunol. 155:5483-5486(1995).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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$ 395.00
Cat# ALS14963
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