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RETN / Resistin Antibody

Mouse Monoclonal Antibody

     
  • WB - RETN / Resistin Antibody ALS14968
    Western Blot (non-reducing) of Resistin antibody ALS14968
    detail
  • WB - RETN / Resistin Antibody ALS14968
    Western Blot (reducing) of Resistin antibody ALS14968
    detail
  • IHC - RETN / Resistin Antibody ALS14968
    Anti-RETN / Resistin antibody IHC of human spleen.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9HD89
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 11kDa
Dilution IHC-P (10 µg/ml), WB (0.2-0.4 µg/ml),
Additional Information
Gene ID 56729
Other Names Resistin, Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, RETN, FIZZ3, HXCP1, RSTN
Target/Specificity Human Resistin
Reconstitution & Storage Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
PrecautionsRETN / Resistin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RETN
Synonyms FIZZ3, HXCP1, RSTN
Function Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells (PubMed:15064728).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q99P87}.
Tissue Location Expressed in white adipose tissue (at protein level) (PubMed:11201732). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood (PubMed:15248836). Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues (PubMed:15064728) Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus (PubMed:15248836)
Research Areas
Citations (0)
citation

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Background

Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.

References

Holcomb I.N.,et al.EMBO J. 19:4046-4055(2000).
Steppan C.M.,et al.Nature 409:307-312(2001).
Kubota T.,et al.Blood 96:3953-3957(2000).
Nohira T.,et al.Eur. J. Endocrinol. 151:151-154(2004).
Rajala M.W.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS14968
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