|Application ||WB, IHC-P, E, IP|
|Reactivity||Human, Mouse, Rat, Bovine|
|Dilution||IHC-P (10 µg/ml), WB (0.5 µg/ml),|
|Other Names||Superoxide dismutase [Cu-Zn], 22.214.171.124, Superoxide dismutase 1, hSod1, SOD1|
|Target/Specificity||Detects 23kD (human) and 19kD (other species) proteins, corresponding to the molecular mass of Cu/Zn superoxide dismutase (SOD) on SDS-PAGE immunoblots.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SOD1 / SOD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|
|Cellular Location||Cytoplasm. Mitochondrion. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Sherman L.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:5465-5469(1983).
Levanon D.,et al.EMBO J. 4:77-84(1985).
Hallewell R.A.,et al.Nucleic Acids Res. 13:2017-2034(1985).
Kajihara J.,et al.J. Biochem. 104:851-854(1988).
Xu Y.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
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