|Application ||WB, IHC-P, E, IP|
|Reactivity||Human, Mouse, Rat, Bovine|
|Dilution||IHC-P (10 µg/ml), WB (0.5 µg/ml),|
|Other Names||Superoxide dismutase [Cu-Zn], 184.108.40.206, Superoxide dismutase 1, hSod1, SOD1|
|Target/Specificity||Detects 23kD (human) and 19kD (other species) proteins, corresponding to the molecular mass of Cu/Zn superoxide dismutase (SOD) on SDS-PAGE immunoblots.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SOD1 / SOD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|
|Cellular Location||Cytoplasm. Mitochondrion. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
Sherman L.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:5465-5469(1983).
Levanon D.,et al.EMBO J. 4:77-84(1985).
Hallewell R.A.,et al.Nucleic Acids Res. 13:2017-2034(1985).
Kajihara J.,et al.J. Biochem. 104:851-854(1988).
Xu Y.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
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