|Application ||WB, IHC-P, E, IP|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Sheep, Xenopus, Bovine, Guinea Pig, Dog|
|Dilution||IHC-P (10 µg/ml), WB (1:1000),|
|Other Names||10 kDa heat shock protein, mitochondrial, Hsp10, 10 kDa chaperonin, Chaperonin 10, CPN10, Early-pregnancy factor, EPF, HSPE1|
|Target/Specificity||Detects ~10 kD protein.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||HSPE1 / HSP10 / Chaperonin 10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
Monzini N.,et al.Biochim. Biophys. Acta 1218:478-480(1994).
Chen J.J.,et al.Biochim. Biophys. Acta 1219:189-190(1994).
Hansen J.J.,et al.Hum. Genet. 112:71-77(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
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