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PIG8 / EI24 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O14681 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39kDa |
| Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 9538 |
|---|---|
| Other Names | Etoposide-induced protein 2.4 homolog, p53-induced gene 8 protein, EI24, PIG8 |
| Target/Specificity | Human EI24. At least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | PIG8 / EI24 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EI24 |
|---|---|
| Synonyms | PIG8 |
| Function | Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity). |
| Cellular Location | Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).
References
Polyak K.,et al.Nature 389:300-306(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gentile M.,et al.Oncogene 20:7753-7760(2001).
Olsen J.V.,et al.Cell 127:635-648(2006).
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