|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Etoposide-induced protein 2.4 homolog, p53-induced gene 8 protein, EI24, PIG8|
|Target/Specificity||Human EI24. At least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||PIG8 / EI24 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).|
|Cellular Location||Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).
Polyak K.,et al.Nature 389:300-306(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gentile M.,et al.Oncogene 20:7753-7760(2001).
Olsen J.V.,et al.Cell 127:635-648(2006).
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