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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SLC38A1 / NaT2 Antibody (clone S104-32)   

SLC38A1 / NaT2 Antibody (clone S104-32)

Mouse Monoclonal Antibody

     
  • IHC - SLC38A1 / NaT2 Antibody (clone S104-32) ALS15000
    Anti-SLC38A1 antibody IHC of human brain, cerebellum, Purkinje.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q9H2H9
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Clone Names S104-32
Calculated MW 54kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 81539
Other Names Sodium-coupled neutral amino acid transporter 1, Amino acid transporter A1, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System N amino acid transporter 1, SLC38A1, ATA1, NAT2, SAT1, SNAT1
Target/Specificity Detects ~50kDa.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsSLC38A1 / NaT2 Antibody (clone S104-32) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC38A1
Synonyms ATA1, NAT2, SAT1, SNAT1
Function Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.
Cellular Location Cell membrane; Multi-pass membrane protein Note=Restricted to the somatodendritic compartment of neurons Found in the cellular processes of neurons in the developing brain (By similarity).
Tissue Location Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.
Volume 50 µl
Research Areas
Citations (0)

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Background

Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.

References

Wang H.,et al.Biochem. Biophys. Res. Commun. 273:1175-1179(2000).
Xu X.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS15000
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