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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLA2G4A Antibody (aa471-520)   

PLA2G4A Antibody (aa471-520)

Rabbit Polyclonal Antibody

     
  • IF - PLA2G4A Antibody (aa471-520) ALS15006
    Immunofluorescence of HUVEC cells, using c-PLA2 Antibody.
  • WB - PLA2G4A Antibody (aa471-520) ALS15006
    Western blot of extracts from HeLa cells, treated with TNF-a 20 ng/ml 30', using c-PLA2 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P47712
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 85kDa
Dilution ELISA (1:10000), IF (1:100-1:500), IHC-P (10 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 5321
Other Names Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA, Phospholipase A2, 3.1.1.4, Phosphatidylcholine 2-acylhydrolase, Lysophospholipase, 3.1.1.5, PLA2G4A, CPLA2, PLA2G4
Target/Specificity c-PLA2 Antibody detects endogenous levels of total c-PLA2 protein.
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsPLA2G4A Antibody (aa471-520) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G4A
Synonyms CPLA2, PLA2G4
Function Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
Cellular Location Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion
Tissue Location Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium
Volume 50 µl
Research Areas
Citations (0)

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Background

Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.

References

Clark J.D.,et al.Cell 65:1043-1051(1991).
Sharp J.,et al.J. Biol. Chem. 266:14850-14853(1991).
Gregory S.G.,et al.Nature 441:315-321(2006).
Lin L.-L.,et al.Cell 72:269-278(1993).
Sharp J.D.,et al.J. Biol. Chem. 269:23250-23254(1994).

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$ 395.00
Cat# ALS15006
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