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Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P47712 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 85kDa |
| Dilution | ELISA (1:10000), IF (1:100-1:500), IHC-P (10 µg/ml), WB (1:500-1:1000) , |
| Gene ID | 5321 |
|---|---|
| Other Names | Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA, Phospholipase A2, 3.1.1.4, Phosphatidylcholine 2-acylhydrolase, Lysophospholipase, 3.1.1.5, PLA2G4A, CPLA2, PLA2G4 |
| Target/Specificity | c-PLA2 Antibody detects endogenous levels of total c-PLA2 protein. |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
| Precautions | PLA2G4A Antibody (aa471-520) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLA2G4A |
|---|---|
| Synonyms | CPLA2, PLA2G4 |
| Function | Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response. |
| Cellular Location | Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion |
| Tissue Location | Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
References
Clark J.D.,et al.Cell 65:1043-1051(1991).
Sharp J.,et al.J. Biol. Chem. 266:14850-14853(1991).
Gregory S.G.,et al.Nature 441:315-321(2006).
Lin L.-L.,et al.Cell 72:269-278(1993).
Sharp J.D.,et al.J. Biol. Chem. 269:23250-23254(1994).
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