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GRM4 / MGLUR4 Antibody (aa851-900)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q14833 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 102kDa |
| Dilution | ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
| Gene ID | 2914 |
|---|---|
| Other Names | Metabotropic glutamate receptor 4, mGluR4, GRM4, GPRC1D, MGLUR4 |
| Target/Specificity | mGluR4 Antibody detects endogenous levels of total mGluR4 protein. |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | GRM4 / MGLUR4 Antibody (aa851-900) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRM4 |
|---|---|
| Synonyms | GPRC1D, MGLUR4 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
References
Makoff A.,et al.Brain Res. Mol. Brain Res. 37:239-248(1996).
Wu S.,et al.Brain Res. Mol. Brain Res. 53:88-97(1998).
Flor P.J.,et al.Neuropharmacology 34:149-155(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
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