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MAGEA1 / MAGE 1 Antibody (aa260-309)

Rabbit Polyclonal Antibody

     
  • WB - MAGEA1 / MAGE 1 Antibody (aa260-309) ALS15053
    Western blot of extracts from HepG2 cells, using MAGE-1 Antibody.
  • IHC - MAGEA1 / MAGE 1 Antibody (aa260-309) ALS15053
    Anti-MAGEA1 / MAGE 1 antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P43355
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 34kDa
Dilution ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 4100
Other Names Melanoma-associated antigen 1, Antigen MZ2-E, Cancer/testis antigen 1.1, CT1.1, MAGE-1 antigen, MAGEA1, MAGE1, MAGE1A
Target/Specificity MAGE-1 Antibody detects endogenous levels of total MAGE-1 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsMAGEA1 / MAGE 1 Antibody (aa260-309) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAGEA1
Synonyms MAGE1, MAGE1A
Function May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas
Volume 50 µl
Research Areas
Citations (0)

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Background

May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

References

van der Bruggen P.,et al.Science 254:1643-1647(1991).
Ding M.,et al.Biochem. Biophys. Res. Commun. 202:549-555(1994).
Wang L.P.,et al.Zhonghua Gan Zang Bing Za Zhi 12:151-155(2004).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS15053
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