Peripherin Antibody (aa421-470)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P41219 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 54kDa |
Dilution | ELISA (1:5000), IHC-P (5 µg/ml), WB (1:500-1:1000) |
Gene ID | 5630 |
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Other Names | Peripherin, Neurofilament 4, PRPH, NEF4, PRPH1 |
Target/Specificity | Peripherin Antibody detects endogenous levels of total Peripherin protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | Peripherin Antibody (aa421-470) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRPH |
---|---|
Synonyms | NEF4, PRPH1 |
Function | Class-III neuronal intermediate filament protein (By similarity). May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network (PubMed:15446584, PubMed:15322088). Assembly of the neuronal intermediate filaments may be regulated by RAB7A (By similarity). Plays a role in the development of unmyelinated sensory neurons (By similarity). May be involved in axon elongation and axon regeneration after injury (By similarity). Inhibits neurite extension in type II spiral ganglion neurons in the cochlea (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, axon {ECO:0000250|UniProtKB:P15331}. Perikaryon {ECO:0000250|UniProtKB:P15331} |
Tissue Location | Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Class-III neuronal intermediate filament protein.
References
Foley J.,et al.Genomics 22:456-461(1994).
Scherer S.E.,et al.Nature 440:346-351(2006).
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