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Peripherin Antibody (aa421-470)

Rabbit Polyclonal Antibody

     
  • WB - Peripherin Antibody (aa421-470) ALS15056
    Western blot of extracts from HepG2 cells, using Peripherin Antibody.
    detail
  • IHC - Peripherin Antibody (aa421-470) ALS15056
    Anti-PRPH / Peripherin antibody IHC of human nerve.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P41219
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Dilution ELISA (1:5000), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 5630
Other Names Peripherin, Neurofilament 4, PRPH, NEF4, PRPH1
Target/Specificity Peripherin Antibody detects endogenous levels of total Peripherin protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsPeripherin Antibody (aa421-470) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRPH
Synonyms NEF4, PRPH1
Function Class-III neuronal intermediate filament protein (By similarity). May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network (PubMed:15446584, PubMed:15322088). Assembly of the neuronal intermediate filaments may be regulated by RAB7A (By similarity). Plays a role in the development of unmyelinated sensory neurons (By similarity). May be involved in axon elongation and axon regeneration after injury (By similarity). Inhibits neurite extension in type II spiral ganglion neurons in the cochlea (By similarity).
Cellular Location Cytoplasm, cytoskeleton. Cell projection, axon {ECO:0000250|UniProtKB:P15331}. Perikaryon {ECO:0000250|UniProtKB:P15331}
Tissue Location Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Class-III neuronal intermediate filament protein.

References

Foley J.,et al.Genomics 22:456-461(1994).
Scherer S.E.,et al.Nature 440:346-351(2006).

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Discontinued
Cat# ALS15056
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