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>   home   >   Products   >   Primary Antibodies   >   HNRNPL / hnRNP L Antibody (aa61-110)   

HNRNPL / hnRNP L Antibody (aa61-110)

Rabbit Polyclonal Antibody

     
  • IF - HNRNPL / hnRNP L Antibody (aa61-110) ALS15103
    Immunofluorescence of HeLa cells, using hnRNP L Antibody.
  • WB - HNRNPL / hnRNP L Antibody (aa61-110) ALS15103
    Western blot of extracts from HeLa/Jurkat/HUVEC cells, using hnRNP L Antibody.
  • IHC - HNRNPL / hnRNP L Antibody (aa61-110) ALS15103
    Anti-HNRNPL / hnRNP L antibody IHC of human small intestine.
  • IHC - HNRNPL / hnRNP L Antibody (aa61-110) ALS15103
    Anti-HNRNPL / hnRNP L antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P14866
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 64kDa
Dilution ELISA (1:20000), IF (1:100-1:500), IHC-P (10 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 3191
Other Names Heterogeneous nuclear ribonucleoprotein L, hnRNP L, HNRNPL, HNRPL
Target/Specificity hnRNP L Antibody detects endogenous levels of total hnRNP L protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsHNRNPL / hnRNP L Antibody (aa61-110) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HNRNPL
Synonyms HNRPL
Function Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PubMed:11809897, PubMed:22570490, PubMed:24164894, PubMed:25623890, PubMed:26051023). Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts (PubMed:2687284). Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (PubMed:11809897).
Cellular Location Nucleus, nucleoplasm. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules
Volume 50 µl
Citations (0)

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Background

Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.

References

Ito M.,et al.Cancer Res. 61:2038-2046(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Pinol-Roma S.,et al.J. Cell Biol. 109:2575-2587(1989).

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$ 395.00
Cat# ALS15103
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