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COX17 Antibody (aa1-50)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q14061 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 7kDa |
| Dilution | ELISA (1:5000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
| Gene ID | 10063 |
|---|---|
| Other Names | Cytochrome c oxidase copper chaperone, COX17 |
| Target/Specificity | COX17 Antibody detects endogenous levels of total COX17 protein. |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | COX17 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | COX17 |
|---|---|
| Function | Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). |
| Cellular Location | Mitochondrion intermembrane space. Cytoplasm |
| Tissue Location | Ubiquitous.. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity).
References
Amaravadi R.,et al.Hum. Genet. 99:329-333(1997).
Punter F.A.,et al.Hum. Genet. 107:69-74(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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