|Application ||IHC-P, IF, E|
|Dilution||ELISA (1:20000), IF (1:100-1:500), IHC-P (10 µg/ml)|
|Other Names||Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 3, 220.127.116.11, 18.104.22.168, C2GnT-mucin type, C2GnT-M, hC2GnT-M, Core 2/core 4 beta-1, 6-N-acetylglucosaminyltransferase, C2/4GnT, GCNT3|
|Target/Specificity||GCNT3 Antibody detects endogenous levels of total GCNT3 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||GCNT3 Antibody (aa226-275) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
Yeh J.-C.,et al.J. Biol. Chem. 274:3215-3221(1999).
Schwientek T.,et al.J. Biol. Chem. 274:4504-4512(1999).
Tan S.,et al.Am. J. Respir. Cell Mol. Biol. 36:737-745(2007).
Ishibashi Y.,et al.Glycoconj. J. 22:53-62(2005).
Huang M.-C.,et al.Oncogene 25:3267-3276(2006).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.