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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HELO1 / ELOVL5 Antibody (aa250-299)   

HELO1 / ELOVL5 Antibody (aa250-299)

Rabbit Polyclonal Antibody

  • WB - HELO1 / ELOVL5 Antibody (aa250-299) ALS15121
    Western blot of extracts from MCF-7 cells, using ELOVL5 Antibody.
  • IHC - HELO1 / ELOVL5 Antibody (aa250-299) ALS15121
    Anti-HELO1 / ELOVL5 antibody IHC of human thymus.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NYP7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 60481
Other Names Elongation of very long chain fatty acids protein 5,, 3-keto acyl-CoA synthase ELOVL5, ELOVL fatty acid elongase 5, ELOVL FA elongase 5, Fatty acid elongase 1, hELO1, Very-long-chain 3-oxoacyl-CoA synthase 5, ELOVL5, ELOVL2
Target/Specificity ELOVL5 Antibody detects endogenous levels of total ELOVL5 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsHELO1 / ELOVL5 Antibody (aa250-299) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ELOVL2
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree
Tissue Location Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain Expressed in the cerebellum.
Volume 50 µl
Research Areas
Citations (0)

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Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.


Leonard A.E.,et al.Biochem. J. 350:765-770(2000).
Suzuki T.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS15121
(40 western blots)
Availability: 5 days
Bulk Size
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