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DDC / DOPA Decarboxylase Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P20711 |
| Reactivity | Human, Rat, Sheep, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54kDa |
| Dilution | IHC-P (1:100), WB (1:1000), |
| Gene ID | 1644 |
|---|---|
| Other Names | Aromatic-L-amino-acid decarboxylase, AADC, 4.1.1.28, DOPA decarboxylase, DDC, DDC, AADC |
| Target/Specificity | Specific for the ~55k DDC protein |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
| Precautions | DDC / DOPA Decarboxylase Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DDC {ECO:0000303|PubMed:15532536, ECO:0000312|HGNC:HGNC:2719} |
|---|---|
| Function | Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin. |
| Tissue Location | [Isoform 2]: High expression in kidney. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
References
Ichinose H.,et al.Biochem. Biophys. Res. Commun. 164:1024-1030(1989).
Scherer L.J.,et al.Genomics 13:469-471(1992).
Sumi-Ichinose C.,et al.Biochemistry 31:2229-2238(1992).
Vassilacopoulou D.S.,et al.Neurochem. Res. 29:1817-1823(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
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