DBH/Dopamine Beta Hydroxylase Antibody (N-Terminus)
Sheep Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P09172 |
Reactivity | Human |
Host | Sheep |
Clonality | Polyclonal |
Calculated MW | 69kDa |
Dilution | IHC-P (1:100), WB (1:1000), |
Gene ID | 1621 |
---|---|
Other Names | Dopamine beta-hydroxylase, 1.14.17.1, Dopamine beta-monooxygenase, Soluble dopamine beta-hydroxylase, DBH |
Target/Specificity | Specific for the ~75k DBH protein in Western blots |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
Precautions | DBH/Dopamine Beta Hydroxylase Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DBH |
---|---|
Function | Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters. |
Cellular Location | [Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Conversion of dopamine to noradrenaline.
References
Humphray S.J.,et al.Nature 429:369-374(2004).
Lamouroux A.,et al.EMBO J. 6:3931-3937(1987).
Kobayashi K.,et al.Nucleic Acids Res. 17:1089-1102(1989).
Li B.,et al.Biochem. J. 313:57-64(1996).
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).
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