|Application ||IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:1000), IF (1:100-1:500), IHC-P (10 µg/ml)|
|Other Names||Latrophilin-2, Calcium-independent alpha-latrotoxin receptor 2, CIRL-2, Latrophilin homolog 1, Lectomedin-1, LPHN2, KIAA0786, LEC1, LPHH1|
|Target/Specificity||LPHN2 Antibody detects endogenous levels of total LPHN2 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||ADGRL2 / LPHN2 Antibody (aa551-600) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others|
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Provided below are standard protocols that you may find useful for product applications.
Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis (By similarity).
White G.R.M.,et al.Oncogene 17:3513-3519(1998).
White G.R.M.,et al.Biochim. Biophys. Acta 1491:75-92(2000).
Hayflick J.S.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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