|Application ||IHC-P, E, Flo|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7|
|Target/Specificity||Dimeric CD27 molecule of approximately 110 kd but does not block the interaction between CD70 and CD27. Clone M-T271 has been shown to abrogate IL-4 production or induce apoptosis in MLR.|
|Reconstitution & Storage||Store at +4°C. DO NOT FREEZE.|
|Precautions||CD27 Antibody (clone M-T271) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Found in most T-lymphocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Camerini D.,et al.J. Immunol. 147:3165-3169(1991).
Loenen W.A.,et al.J. Immunol. 149:3937-3943(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
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