|Application ||IHC-P, E, Flo|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7|
|Target/Specificity||Dimeric CD27 molecule of approximately 110 kd but does not block the interaction between CD70 and CD27. Clone M-T271 has been shown to abrogate IL-4 production or induce apoptosis in MLR.|
|Reconstitution & Storage||Store at +4°C. DO NOT FREEZE.|
|Precautions||CD27 Antibody (clone M-T271) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Found in most T-lymphocytes.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Camerini D.,et al.J. Immunol. 147:3165-3169(1991).
Loenen W.A.,et al.J. Immunol. 149:3937-3943(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
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