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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IQSEC1 Antibody   

IQSEC1 Antibody

Rabbit Polyclonal Antibody

  • IHC - IQSEC1 Antibody ALS15168
    Anti-IQSEC1 antibody IHC of human tonsil, squamous epithelium.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6DN90
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 108kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 9922
Other Names IQ motif and SEC7 domain-containing protein 1, ADP-ribosylation factors guanine nucleotide-exchange protein 100, ADP-ribosylation factors guanine nucleotide-exchange protein 2, Brefeldin-resistant Arf-GEF 2 protein, IQSEC1, ARFGEP100, BRAG2, KIAA0763
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsIQSEC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ARFGEP100, BRAG2, KIAA0763
Function Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.
Cellular Location Cytoplasm. Nucleus. Note=At steady state, may be preferentially cytosolic
Tissue Location Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.
Volume 50 µl
Research Areas
Citations (0)

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In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.


Dunphy J.L.,et al.Curr. Biol. 16:315-320(2006).
Nagase T.,et al.DNA Res. 5:277-286(1998).
Someya A.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:2413-2418(2001).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).

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$ 395.00
Cat# ALS15168
(40 western blots)
Availability: 5 days
Bulk Size
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