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APBA1 / MINT1 Antibody

Rabbit Polyclonal Antibody

     
  • IF - APBA1 / MINT1 Antibody ALS15176
    Immunofluorescence of APBA1 in human brain tissue with APBA1 antibody at 20 ug/ml.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF
Primary Accession Q02410
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 93kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 320
Other Names Amyloid beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Neuron-specific X11 protein, Neuronal Munc18-1-interacting protein 1, Mint-1, APBA1, MINT1, X11
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsAPBA1 / MINT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APBA1
Synonyms MINT1, X11
Function Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.
Cellular Location Cytoplasm. Cytoplasm, perinuclear region Nucleus. Note=Only about 5% of the protein is located in the nucleus
Tissue Location Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen
Research Areas
Citations (0)

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Background

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.

References

Okamoto M.,et al.J. Biol. Chem. 272:31459-31464(1997).
Borg J.-P.,et al.J. Biol. Chem. 273:14761-14766(1998).
Humphray S.J.,et al.Nature 429:369-374(2004).
Duclos F.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:109-113(1993).
Borg J.-P.,et al.Mol. Cell. Biol. 16:6229-6241(1996).

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$ 395.00
Cat# ALS15176
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