|Application ||WB, IHC-P, IP, IHC-Fr, Flo|
|Dilution||IHC-Fr, IHC-P (20 µg/ml),|
|Other Names||Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1, PD1|
|Reconstitution & Storage||2-8 C.|
|Precautions||PDCD1 / CD279 / PD-1 Antibody (clone J116) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors.
Shinohara T.,et al.Genomics 23:704-706(1994).
Finger L.R.,et al.Gene 197:177-187(1997).
Finger L.R.,et al.Gene 203:253-253(1997).
Prokunina L.,et al.Nat. Genet. 32:666-669(2002).
He X.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
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