|Application ||WB, IHC-P, IF, E|
|Other Names||Cholinesterase, 188.8.131.52, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, Pseudocholinesterase, BCHE, CHE1|
|Target/Specificity||Human BCHE / Butyrylcholinesterase. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: immunoelectrophoresis, cross-immunoelectrophoresis, single radial immunodiffusion (Ouchterlony), block ...|
|Reconstitution & Storage||Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze/thaw cycles. Store undiluted.|
|Precautions||BCHE / Cholinesterase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.|
|Tissue Location||Detected in blood plasma (at protein level). Present in most cells except erythrocytes|
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Provided below are standard protocols that you may find useful for product applications.
Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
Prody C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:3555-3559(1987).
McTiernan C.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6682-6686(1987).
Arpagaus M.,et al.Biochemistry 29:124-131(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lockridge O.,et al.J. Biol. Chem. 262:549-557(1987).
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