|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (1:50-1:100),|
|Other Names||2-hydroxyacyl-CoA lyase 1, 4.1.-.-, 2-hydroxyphytanoyl-CoA lyase, 2-HPCL, Phytanoyl-CoA 2-hydroxylase 2, HACL1, HPCL, HPCL2, PHYH2|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||HACL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||HPCL, HPCL2, PHYH2|
|Function||Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.|
|Tissue Location||Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.
Foulon V.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:10039-10044(1999).
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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