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EDNRA / Endothelin A Receptor Antibody (aa378-427)

Rabbit Polyclonal Antibody

  • IF - EDNRA / Endothelin A Receptor Antibody (aa378-427) ALS15255
    Immunofluorescence of LOVO cells, using EDNRA Antibody.
  • WB - EDNRA / Endothelin A Receptor Antibody (aa378-427) ALS15255
    Western blot of extracts from COS7 cells, using EDNRA Antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25101
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Dilution ELISA (1:1000), IF (1:100-1:500), IHC-P (2.5 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 1909
Other Names Endothelin-1 receptor, Endothelin A receptor, ET-A, ETA-R, hET-AR, EDNRA, ETA, ETRA
Target/Specificity EDNRA Antibody detects endogenous levels of total EDNRA protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsEDNRA / Endothelin A Receptor Antibody (aa378-427) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ETA, ETRA
Function Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.
Volume 100 µl
Research Areas
Citations (0)

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Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.


Adachi M.,et al.Biochem. Biophys. Res. Commun. 180:1265-1272(1991).
Cyr C.,et al.Biochem. Biophys. Res. Commun. 181:184-190(1991).
Hosoda K.,et al.FEBS Lett. 287:23-26(1991).
Arai H.,et al.Jpn. Circ. J. 56:1303-1307(1992).
Elshourbagy N.A.,et al.J. Biol. Chem. 268:3873-3879(1993).

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$ 395.00
Cat# ALS15255
(40 western blots)
Availability: 5 days
Bulk Size
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