SST / Somatostatin Antibody (clone YC7)
Rat Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-Fr |
---|---|
Primary Accession | P61278 |
Reactivity | Human, Mouse, Rat, Pig, Guinea Pig |
Host | Rat |
Clonality | Monoclonal |
Clone Names | YC7 |
Calculated MW | 13kDa |
Dilution | IHC-P (1:20) |
Gene ID | 6750 |
---|---|
Other Names | Somatostatin, Growth hormone release-inhibiting factor, Somatostatin-28, Somatostatin-14, SST |
Target/Specificity | Specific for somatostatin. A hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino aci ... |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | SST / Somatostatin Antibody (clone YC7) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SST |
---|---|
Function | [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. |
Cellular Location | Secreted {ECO:0000250|UniProtKB:P60042}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Somatostatin inhibits the release of somatotropin.
References
Shen L.-P.,et al.Proc. Natl. Acad. Sci. U.S.A. 79:4575-4579(1982).
Shen L.-P.,et al.Science 224:168-171(1984).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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