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DUX4 Antibody (clone P2B1)

Mouse Monoclonal Antibody

  • IF - DUX4 Antibody (clone P2B1) ALS15321
    Immunofluorescent staining using P2B1 mouse monoclonal anti-DUX4 N-terminus on C2C12 myoblasts...
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBX2
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names P2B1
Calculated MW 45kDa
Dilution IHC-P (10 µg/ml), WB (1:1000),
Additional Information
Gene ID 100288687;107987484;107987485;107987486;107987487;107987488;107987489;107987490;107987491
Other Names Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}, Double homeobox protein 10 {ECO:0000312|EMBL:AAK91509.1}, DUX4 (HGNC:50800), DUX10
Target/Specificity This antibody recognizeshuman DUX4. It does notcross-react with DUX4c.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsDUX4 Antibody (clone P2B1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUX4 (HGNC:50800)
Synonyms DUX10
Function Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:15709750, ECO:0000269|PubMed:21060811}. Note=Actively transported through the nuclear pore complex (NPC)
Tissue Location Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells
Research Areas
Citations (0)

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Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.


Gabrieels J.,et al.Gene 236:25-32(1999).
Leclercq I.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Oestlund C.,et al.Biochemistry 44:2378-2384(2005).
Mostacciuolo M.L.,et al.Clin. Genet. 75:550-555(2009).

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$ 395.00
Cat# ALS15321
Availability: 5 days
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